Sebaka sa molomo ke microecosystem e rarahaneng e nang le mefuta e fetang 23,000 ea libaktheria tse e pota-potileng.Maemong a mang, libaktheria tsena li ka baka mafu a molomo ka ho toba esita le ho ama bophelo bo botle ka kakaretso. Leha ho le joalo, tšebeliso ea lithibela-mafu e hlahisa mathata a sa tšoaneng, ho kopanyelletsa le ho senyeha ha meriana ka potlako, ho lokolloa, le tsoelo-pele ea lithibela-mafu tse hanyetsang. Lilemong tsa morao tjena, sepheo sa lipatlisiso se se se lebisitse ho nts'etsopele ea lisebelisoa tse kopaneng tse nang le thepa e ntle ea antimicrobial e sebelisang li-nanomaterials. Hajoale, lisebelisoa tsa antibacteria tse thehiloeng ho nanosilver ion le lisebelisoa tsa antibacteria tse thehiloeng ho graphene li sebelisoa hangata 'marakeng.Sehloohong sena, re tla hlahisa mochine oa antibacterial oa graphene le ts'ebeliso indastering ea borashe ba meno.
Graphene ke carbon nanomaterial e mahlakore a mabeli e entsoeng ka liathomo tsa carbon tse hlophisitsoeng ka lesela la hexagonal le sp2 hybridized orbitals.Lintho tse tsoang ho eona li kenyelletsa graphene (G), graphene oxide (GO), le graphene oxide e fokotsehileng (rGO). Li na le likarolo tse ikhethang tsa lik'hemik'hale tse mahlakore a mararo le likarolo tse bohale tsa 'mele. Ho feta moo, li sebetsa e le lijari tse loketseng bakeng sa li-antimicrobial agents, e leng se etsang hore e be tse tšepisang haholo bakeng sa ts'ebeliso e fapaneng masimong a molomo oa antimicrobial.
Melemo eagraphene thepa ea antibacterial
- Tšireletseho le Setsoalle sa Tikoloho, Ha se Chefo: Tšebeliso ea nako e telele ea nanosilver e ka hlahisa mathata a polokeho ka lebaka lapokeletso e ka bang teng le ho falla. Selefera e ngata e ka ba kotsi haholo ho batho le liphoofolong tse anyesang, kaha e ka kena mitochondria, mahe a emolisitsoeng, sebete, tsamaiso ea potoloho le likarolo tse ling tsa 'mele ka ho hema. Boithuto bo bontšitse hore likaroloana tsa nanosilver li bonts'a chefo e matla ha e bapisoa le li-nanoparticles tse ling tsa tšepe tse kang aluminium le khauta. Ka lebaka leo, European Union e boloka boemo bo hlokolosi mabapi le tšebeliso ea thepa ea nanosilver antimicrobial.Ka papiso, lisebelisoa tse thibelang likokoana-hloko tse thehiloeng ho graphene li sebelisa mekhoa e mengata ea ho thibela likokoana-hloko, joalo ka "lithipa tsa nano." Li ka senya ka ho feletseng le ho thibela kholo ea baktheriantle le chefo ea lik'hemik'hale. Lisebelisoa tsena li kopantsoe ka mokhoa o se nang moeli le lisebelisoa tsa polymer, e le ho netefatsaha ho na mokoloto wa dintho tse bonahalang kapa ho falla. Tšireletseho le botsitso ba lisebelisoa tse thehiloeng ho graphene li tiisitsoe hantle. Mohlala, lits'ebetsong tse sebetsang tsa sehlahisoa, lifilimi le mekotla ea PE (polyethylene) e thehiloeng ho graphene e fumane setifikeiti sa ho latela maemo a lijo ho latela Regulation (EU) 2020/1245 European Union.
- Ho tsitsa ha nako e telele: Lisebelisoa tse thehiloeng ho graphene li bontša botsitso bo phahameng le ho tšoarella, ho fana kaPhello ea nako e telele ea antimicrobial ka lilemo tse fetang 10. Sena se tiisa hore thepa ea bona ea antimicrobial e lula e sebetsa ka nako e telele ea tšebeliso, e etsa hore e tšoanelehe bakeng sa tšebeliso ea nako e telele lihlahisoa tsa bohloeki ba molomo.
- Biocompatibility le Safety:Graphene, e le lisebelisoa tse nang le likarolo tse peli tsa khabone, e bonts'a biocompatibility le polokeho e ntle haholo. E lumellana le mefuta e sa tšoaneng ea lisebelisoa tse entsoeng ka resin 'me e ka sebelisoa ka mokhoa o sireletsehileng lihlahisoa tsa tlhokomelo ea molomo ntle le ho baka liphello tse bohloko ho lisele tsa molomo kapa bophelo bo botle ka kakaretso.
- Ts'ebetso ea Broad-Spectrum:Lisebelisoa tse thehiloeng ho graphene li bonts'a ts'ebetso e pharalletseng ea antimicrobial,e khona ho tobisa mefuta e mengata ea libaktheria, ho kenyelletsa le mefuta e 'meli ea Gram-positive le Gram-negative. Ba bonts'itselitekanyetso tsa antibacterial tsa 99.9%khahlanong le Escherichia coli, Staphylococcus aureus, le Candida albicans. Sena se etsa hore li feto-fetohe le ho sebetsa maemong a fapaneng a bophelo bo botle ba molomo.
Mokhoa oa antibacterial oa graphene ke ka tsela e latelang:
Mokhoa oa antibacterial oa graphenee ithutoe haholo ke sehlopha se sebelisanang sa machaba. Ho kenyeletsoa bafuputsi ba tsoang Setsing sa Lipatlisiso sa China sa IBM Watson, le Univesithi ea Columbia. Ba entse tsoelo-pele e kholo ho ithuteng mekhoa ea limolek'hule ea tšebelisano lipakeng tsa graphene le membrane ea lisele tsa baktheria. Lipampiri tsa morao-rao tse mabapi le taba ena li hatisitsoe koranteng ea "Nature Nanotechnology."
Ho ea ka lipatlisiso tsa sehlopha, graphene e na le bokhoni ba ho senya lisele tsa baktheria, e leng se lebisang ho lutla ha lintho tsa intracellular le lefu la baktheria. Se sibolotsoeng sena se fana ka maikutlo a hore graphene e ka sebetsa e le "thibela-mafu" e sa mele. Phuputso e boetse e senola hore graphene ha e ikenye feela ka har'a lisele tsa baktheria, e bakang ho itšeha, empa hape e ntša limolek'hule tsa phospholipid ka ho toba ho tloha lera, kahoo e senya sebopeho sa lera le ho bolaea libaktheria. Liteko tsa elektrone tsa microscopy li fane ka bopaki bo tobileng ba meaho e pharalletseng e se nang letho ka har'a lisele tsa baktheria kamora ho sebelisana le graphene e nang le oxidized, e ts'ehetsang lipalo tsa theory. Ketsahalo ena ea ho ntšoa ha molek'hule ea lipid le ho senyeha ha membrane e fana ka mokhoa o mocha oa limolek'hule oa ho utloisisa cytotoxicity le ts'ebetso ea antibacterial ea nanomaterials. E tla thusa hape lipatlisiso tse ling mabapi le litlamorao tsa tlhaho tsa graphene nanomaterials le ts'ebeliso ea tsona ho biomedicine.
Sesebelisoa sa antibacterial sa graphene indastering ea borashe ba meno:
Ka lebaka la melemo e kaholimo ea lisebelisoa tse kopaneng tsa graphene, mochini oa antibacterial oa graphene le ts'ebeliso li hohetse thahasello e kholo ho tsoa ho bafuputsi le litsebi liindastering tse amanang.
borashe ba meno ba graphene antibacterial, hlahiswa keSehlopha sa MARBON, sebelisa li-bristles tse entsoeng ka mokhoa o khethehileng tse entsoeng ka thepa ea graphene nanocomposite. Kahoo e ka thibela ka katleho kholo le ho ikatisa ha libaktheria, ka hona ho fokotsa kotsi ea mafu a molomo.
Li-bristles li bonolo empa li tiile, li lumella ho hloekisa meno le marenene ha li ntse li sireletsa bophelo bo botle ba enamel le marenene. Borashe ba meno bo boetse bo na le moralo oa ergonomic o fanang ka ts'ebetso e bonolo le ts'ebeliso e bonolo.
Re lumela ka tieo hore borashe ba meno ba antibacteria e tla fana ka boiphihlelo bo ikhethang ba tlhokomelo ea molomo. E ka tlosa ka katleho letlapa la meno le litšila tsa lijo. Ho feta moo, e fana ka tšireletso ea nako e telele ea antibacterial, ho netefatsa hore molomo oa hau o lula o le mocha ebile o phetse hantle.
Qetello:
borashe ba meno ba graphene antibacterial e emela tsoelopele ea morao-rao ts'ebelisong ea lisebelisoa tsa graphene lebaleng la antibacterial. Ka bokhoni ba tsona bo boholo, borashe ba meno ba graphene ba thibelang likokoana-hloko bo reretsoe ho fetola tlhokomelo ea molomo, ho fa batho bophelo bo botle le bo phutholohileng haholoanyane ba tlhokomelo ea molomo. Ha lipatlisiso tsa lisebelisoa tsa graphene li ntse li tsoela pele, borashe ba meno ba graphene ba antibacterial bo tla bapala karolo ea bohlokoa ho khothaletsa bophelo bo botle ba molomo le boiketlo.
Nako ea poso: May-02-2024